Antipsychotic Overdosing and Polypharmacy in Schizophrenic Delinquents Explored

Published on 2019-12-31T13:08:49Z (GMT) by
<div><p>A logistic regression model for 289 cases of schizophrenic offenders in a Swiss forensic hospital between 1995 and 2016 revealed the following factors for above average levels of antipsychotic overdosing and polypharmacy: Odds for overdosing increased in absence of a personality disorder (237%), for each point increase in emotional withdrawal (63.5%) and motor retardation (71.7%), and decreased for poor rapport (42.3%) recorded at admission. Odds for polypharmacy increased with complaints about physicians (157%), for each point increase in IQ (3.6%; range = 65–131, <i>M</i> = 92, <i>SD</i> = 14), reduction of the security level of the ward (36.8%; four levels), and for each point increase in poor attention (27.6%) at admission. It decreased with each previous conviction (10.9%; range = 1–21, <i>M</i> = 3, <i>SD</i> = 2), breaking of rules (46.4%) and the administration of compulsory measures (55.7%) on the ward, a poor legal prognosis (29.4%, four levels), and each point increase in grandiosity (40.3%), passive social withdrawal (42.3%), and depressive symptoms (38.7%) at admission.</p></div>

Cite this collection

Günther, M. P.; Kirchebner, J.; Kling, S.; Lau, S. (2019): Antipsychotic Overdosing and Polypharmacy in Schizophrenic Delinquents Explored. SAGE Journals. Collection. https://doi.org/10.25384/SAGE.c.4801941.v1