A New Chlorinated Phenolic Compound From the Antarctic Lichen, Pertusaria dactylina

Youn, Ui J.

A New Chlorinated Phenolic Compound From the Antarctic Lichen, Pertusaria dactylina

Posted on 2020-03-13 - 12:08

A new chlorinated phenolic compound, methyl-3-chloro-2-hydroxy-4-methoxy-6-pentylbenzoate (1) and 4 known compounds (2-5) were isolated from the Antarctic lichen, Pertusaria dactylina (Pertusariaceae). The structure of the new compound was determined by means of One-dimensional and two dimensional nuclear magnetic resonance (1D and 2D NMR) and high-resolution fast atom bombardment mass spectrometry (HRFABMS) experiments. The antimicrobial activities of compounds 1 to 5 against Staphylococcus aureus and Candida albicans were evaluated. The results showed that compound 1 exhibited a weak inhibitory effect against C. albicans with an IC₅₀ value of 67 ± 7 μg/mL.

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Koo, Man H.; Kim, Min J.; Seo, Jae E.; Kim, Ji H.; Han, Se J.; Kim, Il C.; et al. (2020). A New Chlorinated Phenolic Compound From the Antarctic Lichen, Pertusaria dactylina. SAGE Journals. Collection. https://doi.org/10.25384/SAGE.c.4893264.v1

https://doi.org/10.25384/SAGE.c.4893264.v1

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